Chemical structures of ACT-541468, ACT-605143, and ACT658090. | Download Scientific Diagram
Arithmetic mean (± SD) plasma concentration–time profile of ACT-541468... | Download Scientific Diagram
Nemorexant (ACT-541468) | Cas# 1505484-82-1 - GlpBio
Multiple-dose clinical pharmacology of ACT-541468, a novel dual orexin receptor antagonist, following repeated-dose morning and evening administration - ScienceDirect
daridorexant | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY
Discovery of ORN0829, a potent dual orexin 1/2 receptor antagonist for the treatment of insomnia - ScienceDirect
Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration - Clemens Muehlan ...
Nemorexant (ACT-541468) HCL
Idorsia's Insomnia Drug Meets Primary Endpoint in Phase II Study - Drug Discovery and Development
Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration - Clemens Muehlan ...
Study protocol AC-078A201 Multi-center, double-blind, randomized, placebo-controlled, active-reference, parallel-group, polysomn
Interaction potential of the dual orexin receptor antagonist ACT-541468 with CYP3A4 and food: results from two interaction studies | SpringerLink
Chemical structures of ACT-541468, ACT-605143, and ACT658090. | Download Scientific Diagram
Schematic presentation of the clinical study design for (a) study 1... | Download Scientific Diagram
Chemical structures of ACT-541468, ACT-605143, and ACT658090. | Download Scientific Diagram
Accelerated Development of the Dual Orexin Receptor Antagonist ACTâ•'541468: Integration of a Microtracer in a Firstâ•
Arithmetic mean (± SD) plasma concentration–time profile of ACT-541468... | Download Scientific Diagram
![PDF] The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468 | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/02e95ca9a69340beca1fbf26930dde6c69df1cc8/57-Figure2-1.png "PDF] The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468 | Semantic Scholar")
PDF] The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468 | Semantic Scholar
Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration - Clemens Muehlan ...
Chemical structures of ACT-541468, ACT-605143, and ACT658090. | Download Scientific Diagram
The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist
The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468 | Journal of Pharmacology and Experimental Therapeutics
![PDF] The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468 | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/02e95ca9a69340beca1fbf26930dde6c69df1cc8/61-Figure6-1.png "PDF] The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468 | Semantic Scholar")
PDF] The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468 | Semantic Scholar
![PDF] The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468 | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/02e95ca9a69340beca1fbf26930dde6c69df1cc8/49-Table2-1.png "PDF] The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468 | Semantic Scholar")
PDF] The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468 | Semantic Scholar
The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468 | Journal of Pharmacology and Experimental Therapeutics
Molecules | Free Full-Text | A Comprehensive Review of Daridorexant, a Dual-Orexin Receptor Antagonist as New Approach for the Treatment of Insomnia
