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Discovery of the Potent, Selective, Orally Available CXCR7 Antagonist ACT- 1004-1239 | Journal of Medicinal Chemistry
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Scientific Update on Twitter: "Dr Gabriel Schafer @Idorsia opening day 2 of our conference in Basel talking about development of a stereoselective route for CXR7 antagonist ACT-1004-1239 #OPRDEU22 https://t.co/GmjonCOCgr" / Twitter
![Frontiers | Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data Frontiers | Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data](https://www.frontiersin.org/files/Articles/812065/fphar-13-812065-HTML-r1/image_m/fphar-13-812065-g004.jpg)
Frontiers | Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data
Preclinical development of ACT-1004-1239, a potent and selective CXCR7/ACKR3 antagonist in multiple sclerosis treatment
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Treatment with ACT-1004-1239 dose-dependently increases plasma CXCL11... | Download Scientific Diagram
Preclinical development of ACT-1004-1239, a potent and selective CXCR7/ACKR3 antagonist in multiple sclerosis treatment
![Frontiers | Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data Frontiers | Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data](https://www.frontiersin.org/files/Articles/812065/fphar-13-812065-HTML-r1/image_m/fphar-13-812065-g001.jpg)
Frontiers | Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data
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Reaction pathways at the initial steps of trioxane polymerisation - Catalysis Science & Technology (RSC Publishing) DOI:10.1039/C8CY01691G
![Discovery of the Potent, Selective, Orally Available CXCR7 Antagonist ACT- 1004-1239 | Journal of Medicinal Chemistry Discovery of the Potent, Selective, Orally Available CXCR7 Antagonist ACT- 1004-1239 | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/acs.jmedchem.0c01588/asset/images/large/jm0c01588_0005.jpeg)